| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371036 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Abstract
Trialkylstannanes are versatile precursors for chemical transformations, including radiolabeling with a variety of halogens, particularly iodine. In the present work a convenient, Pd-mediated stannylation method is presented that can be performed in an open flask. The method is selective for aryl iodides allowing selective stannylations in the presence of other halogen atoms. The reaction conditions are mild, making the method compatible with chemically sensitive bioactive compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Julie E. Pickett, András Váradi, Travis C. Palmer, Steven G. Grinnell, Joel M. Schrock, Gavril W. Pasternak, Rashad R. Karimov, Susruta Majumdar,