Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371082 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
SAR studies on the quinolone carboxylic acid class of HIV-1 integrase inhibitors focused on improving the metabolic stability and led to the discovery of 27 and 38.
Graphical abstractSAR studies on the quinoline carboxylic acid class of HIV-1 integrase inhibitors focused on improving the metabolic stability and led to the discovery of 27 and 38.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Johnny Y. Nagasawa, Jenny Song, Huanming Chen, Hong-Woo Kim, Julie Blazel, Samedy Ouk, Bettina Groschel, Virginia Borges, Voon Ong, Li-Tain Yeh, Jean-Luc Girardet, Jean-Michel Vernier, Anneke K. Raney, Anthony B. Pinkerton,