| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371106 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
N-type calcium channels (Cav2.2) have been shown to play a critical role in pain. A series of low molecular weight 2-aryl indoles were identified as potent Cav2.2 blockers with good in vitro and in vivo potency.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sriram Tyagarajan, Prasun K. Chakravarty, Min Park, Bishan Zhou, James B. Herrington, Kevin Ratliff, Randall M. Bugianesi, Brande Williams, Rodolfo J. Haedo, Andrew M. Swensen, Vivien A. Warren, McHardy Smith, Maria Garcia, Gregory J. Kaczorowski,