Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371248 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide riboside is reported. Biological properties of this novel C-nucleoside are also discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rebecca R. Midtkandal, Philip Redpath, Samuel A.J. Trammell, Simon J.F. Macdonald, Charles Brenner, Marie E. Migaud,