| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371414 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
Continuing studies on tetrahydroquinoline glucocorticoid receptor anti-inflammatory agents lead to the identification of several tetrahydroquinolin-3-yl carbamates that exhibited steroid-like activity in in vitro transrepression assays with reduced transactivation of phosphoenol pyruvate carboxykinase (PEPCK), a key enzyme in the gluconeogenesis pathway.
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Related Topics
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Authors
Steven L. Roach, Robert I. Higuchi, Andrew R. Hudson, Angie Vassar, Virginia H.S. Grant, Ryan Lamer, Charlene Hooper, Deepa Rungta, Peter M. Syka, Dale E. Mais, Keith B. Marschke, Lin Zhi,