| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371415 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
We report the synthesis and properties of two new seminaphthorhodafluor (SNARF) derivatives, SNARF-F and SNARF-Cl. Both these derivatives exhibit typical red shifts of absorption and fluorescence, and higher cell permeability as compared to traditional SNARF, while the pH-dependent dual-emission characteristics are well retained. In particular, the lower pKa (7.38) of SNARF-F makes it more suitable than traditional SNARF derivatives for intracellular applications.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eiji Nakata, Yoshijiro Nazumi, Yoshihiro Yukimachi, Yoshihiro Uto, Hiroshi Maezawa, Toshihiro Hashimoto, Yasuko Okamoto, Hitoshi Hori,