| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371491 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The synthesis of a Microcystis aeruginosa predicted metabolite analog of aerucyclamide B was performed. This hexacyclopeptide was obtained from three heterocyclic building blocks by a convergent macrocycle-assembly methodology. The compound exhibited good in vitro antiplasmodial activity (IC50: 0.18 μM, K1, cholorquine resistant strain).
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stella Peña, Laura Scarone, Eduardo Manta, Lindsay Stewart, Vanessa Yardley, Simon Croft, Gloria Serra,