Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371502 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
Synthesis of four water-soluble resveratrol and piceatannol derivatives bearing symmetrically branched glyceryl trimer (BGL003) with a non-biocleavable linkage, and their biological evaluation as a mitochondrial fusion-inducing agent with cellular fat-reducing effect from cells, is described. The effect of Piceatannol–BGL003 conjugate was as high as that of original stilbenoids.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hisao Nemoto, Ayato Katagiri, Masaki Kamiya, Tsuyoshi Matsushita, Hatsuhiko Hattori, Kosuke Matsumura, Tomohiro Itou, Tomoyuki Kawamura, Toshiyuki Kita, Hana Nishida, Naokatu Arakaki,