| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371506 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The discovery, optimization and structure–activity relationship of novel FATP1 inhibitors have been described. The detailed SAR studies of each moiety of the inhibitors combined with metabolite analysis led to the identification of the potent inhibitors 11p and 11q with improved blood stability.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tetsuyoshi Matsufuji, Mika Ikeda, Asuka Naito, Masakazu Hirouchi, Hideo Takakusa, Shoichi Kanda, Masanori Izumi, Jun Harada, Tsuyoshi Shinozuka,