Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371638 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
As a prelude to efforts to identify schweinfurthin binding proteins, an ester conjugate and an amide conjugate of schweinfurthin F and biotin have been prepared by chemical synthesis. These compounds maintain activity in SF-295 cells comparable to the parent system, and display the lower potency in A549 cells that is a characteristic of the schweinfurthin pattern of activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natalie C. Ulrich, Craig H. Kuder, Raymond J. Hohl, David F. Wiemer,