Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371680 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The synthesis of several pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine analogs is described with one such analog possessing subnanomolar potency in both genotype 1a and 1b cell culture HCV replicon assays.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A. Chris Krueger, Darold L. Madigan, David W. Beno, David A. Betebenner, Robert Carrick, Brian E. Green, Wenping He, Dachun Liu, Clarence J. Maring, Keith F. McDaniel, Hongmei Mo, Akhteruzzaman Molla, Christopher E. Motter, Tami J. Pilot-Matias,