| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371840 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Dihydroindolo[2,1-a]isoquinolines were synthesized from tetrahydroisoquinolines and α-fluoroaldehydes by a novel two-step procedure. These compounds exhibited significant immunosuppressive activity against IL-2, IL-10 and IFN-γ.
Graphical abstractDihydroindolo[2,1-a]isoquinolines were synthesized from tetrahydroisoquinolines and α-fluoroaldehydes by a novel two-step procedure. These compounds exhibited significant immunosuppressive activity against IL-2, IL-10 and IFN-γ.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![A direct synthesis of 5,6-dihydroindolo[2,1-a]isoquinolines that exhibit immunosuppressive activity](/preview/png/1371840.png "First Page Preview: A direct synthesis of 5,6-dihydroindolo[2,1-a]isoquinolines that exhibit immunosuppressive activity")
Authors
George A. Kraus, Vinayak Gupta, Marian Kohut, Navrozedeep Singh,