| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371862 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Fully automated synthesis and initial PET evaluation of a TSPO radioligand, [11C]PBR28 (N-(2-[11C]methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide), are reported. These results facilitate the potential preclinical and clinical PET studies of [11C]PBR28 in animals and humans.
Graphical abstractFully automated synthesis and initial PET evaluation of a TSPO radioligand [11C]PBR28 are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Fully automated synthesis and initial PET evaluation of [11C]PBR28](/preview/png/1371862.png "First Page Preview: Fully automated synthesis and initial PET evaluation of [11C]PBR28")
Authors
Min Wang, Karmen K. Yoder, Mingzhang Gao, Bruce H. Mock, Xiao-Ming Xu, Andrew J. Saykin, Gary D. Hutchins, Qi-Huang Zheng,