| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371868 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A series of 3,4-diarylthiazol-2(3H)-ones and three 3,4-diarylthiazol-2(3H)-imines were synthesized and evaluated for their cytotoxicity in a panel of human cancer cell lines. Compounds 21 and 22 showed potential anticancer activity against human CEM cells with IC50 values of 0.12 and 0.24 μM, respectively.
Graphical abstractA series of 3,4-diarylthiazol-2(3H)-ones and three 3,4-diarylthiazol-2(3H)-imines were synthesized and evaluated for their cytotoxicity in a panel of human cancer cell lines.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zong-Ying Liu, Yue-Ming Wang, Zhuo-Rong Li, Jian-Dong Jiang, David W. Boykin,