Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371872 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
The synthesis and structure–activity relationship studies of 1,4,5,6-tetrahydropyridazines are described. The target compounds 3–5 represent a novel class of potent and selective CB1 receptor antagonists.
Graphical abstractTetrahydropyridazines represent a novel class of potent CB1 receptor antagonists.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jos H.M. Lange, Arnold P. den Hartog, Martina A.W. van der Neut, Bernard J. van Vliet, Chris G. Kruse,