Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371873 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
Novel compounds were prepared that united the pharmacologies of the μ-opioid tramadol with the 5-HT4 agonists metoclopramide and norcisapride. The synthesis, chiral separation and in vitro activity of the new compounds is described.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Liming Shao, Fengjiang Wang, Michael C. Hewitt, Timothy J. Barberich,