| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371885 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Three new humulane-type sesquiterpenes, 8-O-(p-coumaroyl)-5β-hydroperoxy-1(10)E,4(15)-humuladien-8α-ol (1), 8-O-(3-nitro-p-coumaroyl)-1(10)E,4(15)-humuladien-5β,8α-diol (2) and 8-O-(p-coumaroyl)-1(10)E,4(5)E-humuladien-8-ol (3), and a new copaborneol derivative, 1-O-p-coumaroyl-copaborneol (4), have been isolated from the methanol extract of Pileacavaleriei Lévl. subsp. crenata C. J. Chen. Their structures were elucidated using spectroscopic methods. Cytotoxic and antimicrobial activities of the isolated compounds were evaluated.
Graphical abstractThree new humulane-type sesquiterpenes 1–3, and a copaborneol derivative 4 were isolated from the methanol extract of Pileacavaleriei subsp. crenata. Their structures were elucidated and cytotoxic activities were evaluated.Figure optionsDownload full-size imageDownload as PowerPoint slide
