| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371925 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Four novel water-soluble lipid immunoadjuvants were designed, synthesized and characterized by MS and NMR. They all induce mouse dendritic cell maturation and B cell proliferation. We demonstrate that in spite of the chemical modification, the four compounds remain TLR2 agonists.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maria Vittoria Spanedda, Béatrice Heurtault, Steffen Weidner, Corinne Baehr, Emmanuelle Boeglin, Julien Beyrath, Sara Milosevic, Line Bourel-Bonnet, Sylvie Fournel, Benoît Frisch,