Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1371928 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.
Graphical abstractA series of carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities.Figure optionsDownload full-size imageDownload as PowerPoint slide