| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371931 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
A series of amide derived β3-adrenergic receptor (AR) agonists is described. The discovery and optimization of several series of compounds derived from 1, is used to lay the SAR foundation for second generation β3-AR agonists for the treatment of overactive bladder.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stephen D. Goble, Liping Wang, K. Lulu Howell, Alka Bansal, Richard Berger, Linda Brockunier, Jerry DiSalvo, Scott Feighner, Bart Harper, Jiafang He, Amanda Hurley, Donna Hreniuk, Emma Parmee, Michael Robbins, Gino Salituro, Anthony Sanfiz,