| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371997 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
By using podophyllotoxin as a lead compound, eight novel esters of 2-chloropodophyllotoxin were designed, semisynthesized, and preliminarily evaluated for their insecticidal activity against the pre-third-instar larvae of Mythimna separata Walker in vivo for the first time. Among all the tested compounds, especially three esters of 2-chloropodophyllotoxin 8a, 8c, and 8g, and one intermediate 6 showed more promising and pronounced insecticidal activity than toosendanin, a commercial insecticide derived from Melia azedarach.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hui Xu, Xiao Xiao,