| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372016 | Bioorganic & Medicinal Chemistry Letters | 2009 | 6 Pages |
Abstract
Diterpenes are a structural class of molecules that are derived from four isoprene subunits and are widespread throughout nature. A number of neoclerodane diterpenes have been found to have biological activity but a limited number of chemical investigations have been conducted. Recently, the neoclerodane diterpene, salvinorin A (12) has been investigated due to its unique pharmacological profile. This review will discuss the chemical methods used to chemically modify and synthesize 12.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anthony Lozama, Thomas E. Prisinzano,