| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372040 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Two ethylene linked binuclear mixed ferrocene/ruthenium complexes were biologically investigated in comparison to structurally related mononuclear ferrocene or ruthenium species with styryl substituents or ligands. Results indicated that the electron distribution (but not the redox potential), cellular uptake and (to some minor extent) anti-estrogenic effects were the key contributors to antiproliferative effects observed in tumor cell lines.
Graphical abstractMixed ferrocene/ruthenium bioorganometallics.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ingo Ott, Konrad Kowalski, Ronald Gust, Jörg Maurer, Philipp Mücke, Rainer F. Winter,