Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1372071 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
This study to investigate anti-influenza components from the bark of Alnus japonica resulted in the isolation of two rare acylated diarylheptanoids, named oregonoyl A (5) and oregonoyl B (6), along with nine known compounds (1–4 and 7–11). Their structures were elucidated on the basis of extensive spectroscopic and chemical methods. Antiviral testing of compounds 1–11 against KBNP-0028 (H9N2) avian influenza virus showed that platyphyllone (10) was strongly active, and platyphyllonol-5-xylopyranoside (9) was moderately active against KBNP-0028 as compared with the positive control, zanamivir, respectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nguyen Huu Tung, Hyuk-Joon Kwon, Jae-Hong Kim, Jeong Chan Ra, Yan Ding, Jeong Ah Kim, Young Ho Kim,