Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1372110 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Based on structural information for a peptide (P8-2KAQ) that binds to granulocyte-colony stimulating factor receptor (G-CSFR), small ligands with a biaryl scaffold were designed and their binding affinities were evaluated.
Graphical abstractThe synthesis of ligand 4 binds to G-CSF receptor is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Radwan El-Haggar, Ken Kamikawa, Kazuya Machi, Zhengmao Ye, Yuko Ishino, Takeshi Tsumuraya, Ikuo Fujii,