| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372128 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Structure-guided design led to the discovery of novel chemical scaffolds for B-Raf inhibitors. Both type I and type II kinase inhibitors have been explored and lead compounds with good potency and excellent selectivity have been identified.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaolun Wang, Edward J. Salaski, Dan M. Berger, Dennis Powell, Yongbo Hu, Donald Wojciechowicz, Karen Collins, Eileen Frommer,