| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372151 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
1,3,4-Oxadiazole derivatives were found to enhance astrocyte differentiation in rat fetal neural stem cells (NSCs). Differentiation activity was assessed by immunocytochemistry and analysis of mRNA expression of astrocyte markers, GFAP and S100. Compounds 7 and 8 showed approximately a two-fold increase in astrocyte differentiation without engagement of neuronal differentiation and detectable cytotoxicity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dong Jo Chang, Mi Young Jeong, Jiho Song, Chang Yun Jin, Young-Ger Suh, Hyun-Jung Kim, Kyung Hoon Min,