| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372178 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
A series of triazolopyridazines substituted with methylisoquinolinone were designed and synthesized. Some of the triazolopyridazines strongly inhibited c-Met kinase and showed good anti-proliferative activity against a panel of c-Met-amplified gastric cancer cell lines (MKN-45, SNU-5 and Hs746T).
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jae Wook Ryu, Sun-Young Han, Jeong In Yun, Sang-Un Choi, Heejung Jung, Jae Du Ha, Sung Yun Cho, Chong Ock Lee, Nam Sook Kang, Jong Sung Koh, Hyoung Rae Kim, Jongkook Lee,