| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372203 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
Substituted benzimidazoles were profiled as inhibitors of kinesin spindle protein (KSP), an increasingly important target for the development of anticancer drugs. This series demonstrated the monoastral phenotypic response and was found to be active in both enzymatic and cellular-based assays.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Brian R. Lahue, Yao Ma, Gerald W. Shipps Jr., Wolfgang Seghezzi, Ronald Herbst,