Article ID Journal Published Year Pages File Type
1372230 Bioorganic & Medicinal Chemistry Letters 2009 4 Pages PDF
Abstract

Phytochemical investigations on the CHCl3-soluble fraction of the whole plant of Duranta repens Linn. led to the isolation of four new coumarinolignoids, Repenins A–D (1–4), along with the known coumarinolignoids, cleomiscosin A (5) and durantin A (6). Their structures were determined by modern spectroscopic analysis including 1D and 2D NMR techniques and chemical studies. The compounds (1–6) showed potent antioxidative scavenging activity against DPPH radicals, with IC50 values in the range 0.420–0.625 mM. Repenin B (2) displayed the strongest scavenging potential with IC50 values of (0.420 mM).

Graphical abstractStructures and important mass fragmentation pattern of coumarinolignoids (1–6).Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , ,