| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372301 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
It was demonstrated in our studies that norfloxacin, a representative member of quinolone antibiotics, can indeed stabilize the gyrase–DNA complex formed during enzymatic cycle. In addition, the formation of the drug-induced complex has been firstly visualized through our atomic force microscopic examination.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hao Zhang, Juanjuan Guo, Dawei Li, Magdeline Tao Tao Ng, Jasmine Yiqin Lee, Bei Lv, Chee Wee Ng, Selvi Lee, Fangwei Shao, Tianhu Li,