Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1372423 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Correlation of structural features of selected N-phenyl piperidine derivatives 3 with integrin α5β1 binding affinities and selectivities as well as pharmacokinetic properties are described. The best compounds were compared in pharmacokinetic studies in rat.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gunther Zischinsky, Frank Osterkamp, Doerte Vossmeyer, Grit Zahn, Dirk Scharn, Ariane Zwintscher, Roland Stragies,