| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372450 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
From our modulator library an interesting inhibitor of breast cancer resistance protein (BCRP) was identified. Due to its high inhibitory potency, this compound may serve as a promising novel lead for the design of new and potent modulators. This adds a new structural class to the few known highly active BCRP inhibitors.
Graphical abstractCompound 5 is a novel lead for the design of new and potent BCRP modulators.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anne Pick, Henrik Müller, Michael Wiese,