| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372465 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A diverse group of novel medium ring heterocycles derived from naturally abundant proteinogenic amino acids were evaluated for their potency towards antithrombotic activity. The more potent benzofused oxazepine and oxazocine scaffolds were diversified by incorporating different amino acids at the position number 3. Further the effect of ring size has also been taken into account and it was observed that the eight-membered oxazocines ane more potent compared to the corresponding oxazepines.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jitendra Kumar Mishra, Krishnananda Samanta, Manish Jain, Madhu Dikshit, Gautam Panda,