Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1372519 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
A series of p-hydroxybenzenesulphonamides ERβ receptor agonists were discovered and several compounds identified had excellent selectivity over the related ERα receptor. One of these, compound 11, had an interesting binding conformation determined by X-ray and represents an excellent starting point in the quest for further selective ERβ agonists.
Graphical abstractA series of p-hydroxybenzenesulphonamides ERβ receptor agonists were discovered and several compounds identified had excellent selectivity over the related ERα receptor. One of these, compound 11, had an interesting binding conformation determined by X-ray and represents an excellent starting point in the quest for further selective ERβ agonists.Figure optionsDownload full-size imageDownload as PowerPoint slide