| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372625 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
Novel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity.
Graphical abstractPharmacological activities of powerful Tetrac analogs were found.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alexandre Bridoux, Huadong Cui, Evgeny Dyskin, Murat Yalcin, Shaker A. Mousa,