| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372690 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
This paper describes a series of modifications of the side chain of micromolide, an anti-tuberculosis natural product. Most of the synthesized compounds showed significantly decreased activities, which suggests that the long aliphatic side chain of micromolide and its double bond are essential to its activity.
Graphical abstractThis paper describes a series of modifications of the side chain of micromolide, an anti-tuberculosis natural product. Most of the synthesized compounds showed significantly decreased activities, which suggests that the long aliphatic side chain of micromolide and its double bond are essential to its activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hai Yuan, Rong He, Baojie Wan, Yuehong Wang, Guido F. Pauli, Scott G. Franzblau, Alan P. Kozikowski,