| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372780 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
A series of benzothiophene methyl amines were examined in an effort to identify non-amidine chemotypes with reduced polypharmacology from existing leads with the goal of finding potent ASIC3 channel blockers to advance the therapeutic evaluation of ASIC3 inhibition.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Scott D. Kuduk, Ronald K. Chang, Christina N. Di Marco, Robert M. DiPardo, Sean P. Cook, Matthew J. Cato, Aneta Jovanovska, Mark O. Urban, Michael Leitl, Robert H. Spencer, Stefanie A. Kane, George D. Hartman, Mark T. Bilodeau,