| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372818 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David A. Scott, Brian M. Aquila, Geraldine A. Bebernitz, Donald J. Cook, Les A. Dakin, Tracy L. Deegan, Maureen M. Hattersley, Stephanos Ioannidis, Paul D. Lyne, Charles A. Omer, Minwei Ye, XiaoLan Zheng,