| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372908 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.
Graphical abstractThis Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists](/preview/png/1372908.png "First Page Preview: Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists")
Authors
Alexander Pasternak, Stephen D. Goble, Reynalda K. deJesus, Donna L. Hreniuk, Christine C. Chung, Michael R. Tota, Paul Mazur, Scott D. Feighner, Andrew D. Howard, Sander G. Mills, Lihu Yang,