Article ID Journal Published Year Pages File Type
1372931 Bioorganic & Medicinal Chemistry Letters 2011 4 Pages PDF
Abstract

Highly selective luminescent probes, QLUC-TYR and LUC-GLU, for detection of carboxypeptidase activity were synthesized. Caged substrates were first cleaved by corresponding carboxypeptidases, and then they were activated by luciferase to emit light. Enzymatic activities of biologically important carboxypeptidases can be determined using this technology.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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