Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1372931 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Highly selective luminescent probes, QLUC-TYR and LUC-GLU, for detection of carboxypeptidase activity were synthesized. Caged substrates were first cleaved by corresponding carboxypeptidases, and then they were activated by luciferase to emit light. Enzymatic activities of biologically important carboxypeptidases can be determined using this technology.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yu-Cheng Chang, Pei-Wen Chao, Ching-Hsuan Tung,