| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1372954 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
A series of N-formyl hydroxylamine peptide deformylase inhibitors containing a cyclic azaamino acid moiety between the P1′ and P3′ substituents are presented. Selected compounds display antibacterial activity against pathogens associated with respiratory tract infections with representative compounds showing excellent MICs against Haemophilus influenzae.
Graphical abstractA series of N-formyl hydroxylamine peptide deformylase inhibitors (I) containing a cyclic azaamino moiety between the P1′ and P3′ substituents are presented. Selected compounds display antibacterial activity against pathogens associated with respiratory tract infections with representative compounds showing excellent MICs against Haemophilus influenzae.Figure optionsDownload full-size imageDownload as PowerPoint slide
