| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373009 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
Radiolytic transformation of the isoflavonoid rotenone (1) with γ-irradiation afforded two new degraded products, rotenoisins A (2) and (3). The structures of the two new rotenone derivatives were elucidated on the basis of spectroscopic methods. The new products 2 and 3 exhibited significantly enhanced inhibitory activities against pancreatic lipase and adipocyte differentiation in 3T3-L1 cells when compared to parent rotenone.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chul-Hong Park, Byung Yeoup Chung, Seung Sik Lee, Hyoung-Woo Bai, Jae Young Cho, Cheorun Jo, Tae Hoon Kim,