Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373060 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Symmetrically and asymmetrically substituted 1,2,4,5-tetraoxanes were synthesized by the oxidative system H2O2/TFE in presence of MeReO3 as a catalyst. All of the synthesized compounds were characterized spectroscopically, and evaluated for cytotoxicity, and antimalarial activity. Several of these tetraoxanes exhibited in vitro antimalarial activity without showing any cytotoxicity. Thermal stability of these compounds was studied by differential scanning calorimetry.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Himanshu Atheaya, Shabana I. Khan, Ritu Mamgain, Diwan S. Rawat,