Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373099 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A small set of 9-aminoacridine-3- and 4-carboxamides were synthesized efficiently using the benzyne/azide click chemistry. The products bind to duplex DNA but have different antitumour activity in the HL60 cell line.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lesley A. Howell, Aaron Howman, Maria A. O’Connell, Anja Mueller, Mark Searcey,