| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373223 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
The design and profile of a series of indole containing long acting β2-adrenoceptor agonists is described. Evaluation of these analogues using an in vitro guinea pig trachea tissue model demonstrates that analogues within this series have salmeterol-like duration of action with potential for long duration of action in humans.
Graphical abstractThe design and profile of a series of indole containing long acting β2-adrenoceptor agonists is described. Evaluation of these analogues using an in vitro guinea pig trachea tissue model demonstrates that analogues within this series have salmeterol-like duration of action with potential for long duration of action in humans.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alan D. Brown, Mark E. Bunnage, Paul A. Glossop, Mark Holbrook, Rhys D. Jones, Charlotte A.L. Lane, Russell A. Lewthwaite, Simon Mantell, Christelle Perros-Huguet, David A. Price, Rob Webster,