| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373251 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Neutral 5-substituted 4-anilinoquinazolines addressed high in vivo clearance and phospholipidosis associated with previous basic compounds such as 3, and a representative compound 8a inhibited tumor growth in a mouse xenograft model when co-administered with the cytochrome P450 inhibitor 1-aminobenzotriazole (ABT).
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Peter Ballard, Bernard C. Barlaam, Robert H. Bradbury, Allan Dishington, Laurent F.A. Hennequin, D. Mark Hickinson, Ian M. Hollingsworth, Jason G. Kettle, Teresa Klinowska, Donald J. Ogilvie, Stuart E. Pearson, James S. Scott, Abid Suleman,