Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373263 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A facile, one-pot synthesis of thio and selenourea derivatives from amines using tetrathiomolybdate 1 and tetraselenotungstate 2 as sulfur and selenium transfer reagents, respectively, is reported. The compounds were tested for their activity as urease inhibitors and some of the compounds showed potent activity in the nanomolar range towards jack bean urease.
Graphical abstractA facile, one-pot synthesis of thio and selenourea derivatives is reported. Some of the derivatives showed potent inhibitory activity against urease (jack bean) in the nanomolar range.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kirubakaran Sivapriya, Perumal Suguna, Arun Banerjee, Vadivelu Saravanan, Desirazu N. Rao, Srinivasan Chandrasekaran,