Article ID Journal Published Year Pages File Type
1373263 Bioorganic & Medicinal Chemistry Letters 2007 5 Pages PDF
Abstract

A facile, one-pot synthesis of thio and selenourea derivatives from amines using tetrathiomolybdate 1 and tetraselenotungstate 2 as sulfur and selenium transfer reagents, respectively, is reported. The compounds were tested for their activity as urease inhibitors and some of the compounds showed potent activity in the nanomolar range towards jack bean urease.

Graphical abstractA facile, one-pot synthesis of thio and selenourea derivatives is reported. Some of the derivatives showed potent inhibitory activity against urease (jack bean) in the nanomolar range.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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