| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373293 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
A variety of novel aminoheterocycle scaffolds as selective monoamine reuptake inhibitors have been prepared and one of these scaffolds is achiral. The main elements responsible for hERG channel, CYP2D6 and CYP3A4 inhibition were identified.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Matthew C. Lucas, David S. Carter, Hai-Ying Cai, Eun Kyung Lee, Ryan C. Schoenfeld, Sandra Steiner, Marzia Villa, Robert J. Weikert, Pravin S. Iyer,