Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1373301 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
The interaction between polyethylenimine (PEI) and telomeric DNA was studied. The results demonstrated that PEI could effectively induce, stabilize, and regulate intramolecular G-quadruplexes. The mechanism for these results has been discussed, and was estimated to be condensation effect of PEI.
Graphical abstractGeneral scheme of the formation of G-quadruplexes by PEI condensation.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hongxia Sun, Qiuju Zhou, Junfeng Xiang, Yalin Tang,